A Turning Point For Gene Therapy: What One Tragic Event Reveals About The Promise And Peril Of Genetic Medicine

A patient death in a CRISPR trial halts gene editing studies, raising critical safety questions. What this means for the ...
eLife

Separating selection from mutation in antibody language models

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...
eLife

A differentiable model for optimizing the genetic drivers of synaptogenesis

This study presents SynaptoGen, a differentiable extension of connectome models that links gene expression, protein-protein interaction probabilities, synaptic multiplicity, and synaptic weights, and ...
Modern Engineering Marvels on MSN

Hidden DNA weak spot near gene start mutates rapidly

These sequences are extremely prone to mutations and rank among the most functionally important regions in the entire human genome, together with protein-coding sequences,” said Donate Weghorn, a ...
IEEE

Genetic Algorithm-Optimized Feature Selection for sEMG-IMU Fusion Improves Intention Detection in AI-Driven Robotic Walking System

Abstract: The increasing demand for responsive and intuitive assistive walking devices, driven by an aging population, underscores the need for intelligent systems powered by emerging machine learning ...
Frontiers

Hybrid genetic algorithm and Q-learning-based solution for the time-variant berth and quay crane allocation problem

Institute of Logistics Science and Engineering of Shanghai Maritime University, Pudong, China Introduction: This study addresses the joint scheduling optimization of continuous berths and quay cranes ...
Frontiers

Multi-source data recognition and fusion algorithm based on a two-layer genetic algorithm–back propagation model

1 The College of Computer, Qinghai Normal University, Xining, China 2 Department of Mechanical and Electrical Engineering, College of Xining Urban Vocational and Technical, Xining, China Traditional ...
GitHub

Portfolio Genetic Optimization Algorithm

This repository contains the MATLAB implementation of a genetic algorithm to optimize stock portfolios based on their Sharpe Ratio. The algorithm employs evolutionary principles such as selection, ...
IEEE

Prediction of Essential Proteins Using Genetic Algorithm as a Feature Selection Technique

Abstract: Essential proteins play a vital role in the preparation of antibiotics, disease diagnosis, and understanding the structure of an organism. It is crucial for cell survival and is associated ...
The New York Times

Amy Klobuchar Wants to Stop Algorithms From Ripping You Off

This week I interviewed Senator Amy Klobuchar, Democrat of Minnesota, about her Preventing Algorithmic Collusion Act. If you don’t know what algorithmic collusion is, it’s time to get educated, ...