How major nuclear protein complexes control specialized gene regulation in cancer and beyond

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...
Nature

Transcription articles from across Nature Portfolio

Transcription is the process by which an RNA polymerase synthesizes ribonucleic acid (RNA) using deoxyribonucleic acid (DNA) as a template. The existing ENCODE registry of candidate human and mouse ...
Nature

Transcription factors articles from across Nature Portfolio

Transcription factors are proteins that bind to DNA to regulate gene expression via transcription: the process by which the genetic code generates mRNAs or small RNAs. Transcription factors operate by ...
eLife

Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with nuclear speckles

HIV hijacks SRRM2 to enlarge nuclear speckles, stabilizing CPSF6 puncta and promoting efficient viral replication.
2UrbanGirls on MSN

The race for cellular reprogramming: How one biotech built phase 3-level evidence while billion-dollar competitors remain in the lab

Jonas Salk quietly built the polio vaccine through rigorous, methodical work in Pittsburgh: treating patients, refinin ...