Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Scientists at Duke-NUS Medical School have developed two powerful computational tools that could transform how researchers study the "conversations" between cells inside the body. The tools, called ...

Triglia discusses her research at the intersection of genetics, epigenetics, single-cell genomics and computational biology.

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

This article explores how single-cell multiomics and spatial transcriptomics are illuminating early pregnancy, uncovering maternal fetal cell interactions and paving the way for better understanding ...

Immune low-response states significantly impact the effectiveness of immunotherapy in cancer treatment. These states ...