Scientists have uncovered key new information towards understanding the crucial first step in protein synthesis, the process by which the genetic code, harbored within DNA and copied into RNA, is ...

Scientists at the University of California, Santa Cruz, have trapped the ribosome, a protein-building molecular machine essential to all life, in a key transitional state that has long eluded ...

A series of structures of the eukaryotic protein-synthesis machinery are imaged at high resolution in defined states of the elongation phase of protein synthesis. Analysis suggests that there are ...

An international team of scientists have used advanced microscopy to image how ribosomes recruit to mRNA. Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell ...

Chemists from ETH Zurich have found a way to produce poorly soluble proteins by caging a uniquely reactive boron compound. This method opens up new possibilities for the synthesis of tailored protein ...

With the principles of molecular biology very much in the zeitgeist these days, we thought it would be handy to provide some sort of visual aid to help our readers understand the complex molecular ...

Cryo-EM structure of the Giardia ribosome reveals a highly compact, GC-rich rRNA with eukaryotic r-proteins. (A) Structure of the Giardia ribosome with all the r-proteins colored (SSU, shades of blue ...

Researchers demonstrated how amino acids could spontaneously attach to RNA under early Earth-like conditions using thioesters, providing a long-sought clue to the origins of protein synthesis. This ...

Scientists from Uppsala University have used cryo-electron microscopy to reveal details of the protein synthesis mechanism in the parasite Giardia intestinalis, which causes diarrhoeal disease. The ...