Researchers have used cryo- electron microscopy to elucidate for the first time the structure and function of a very small enzyme embedded in cell membranes. This enzyme builds complex sugar trees ...

SANTA CRUZ, CA — Researchers at the University of California, Santa Cruz, have determined the three-dimensional structure of an RNA enzyme, or “ribozyme,” that carries out a fundamental reaction ...

While most enzymatic activity is conducted through chemical binding interactions between molecules, in some cases, the mere presence of an enzyme can affect intracellular functions. While exploring ...

Chemical structure for thiamine pyrophosphate and protein structure of transketolase. Thiamine pyrophosphate cofactor in yellow and xylulose 5-phosphate substrate in black. Credit: Thomas ...

A new method has enabled the natural structure of particularly large and complex enzymes to be revealed. Scientists have investigated a multi-enzyme complex that plays an essential role in metabolism ...

Researchers have found that peroxiredoxins, a family of antioxidant enzymes central to how cells manage oxidative stress, can assemble into a far wider variety of molecular shapes than scientists ...

Macrolides are an important class of antibiotics that includes drugs such as azithromycin and erythromycin, which are widely used to treat a range of infections, including pneumonia and skin ...

"This structure answers a long-standing question for how two essential regions, N-lip and C-lip, which are located on opposite ends of this protein in humans, come together to form a function enzyme ...

David Cantu and Tin Nguyen have received a 3-year, $599,999 grant from the National Science Foundation’s Cyberinfrastructure for Sustained Scientific Innovation (CSSI) Program to support the creation ...