Similarly to the artistic technique of folding paper into ornate shapes, DNA origami is a self-assembling technique of precisely folding single-stranded DNA scaffolds into well-defined nanostructures.

DNA origami sounds like science fiction, but for HIV vaccine researchers it is becoming a practical design tool. By folding strands of DNA into tiny three-dimensional scaffolds, scientists can arrange ...

DNA, the medium of life, is so deeply associated with the biochemical world that considering its nonbiological applications may seem far-fetched. However, for researchers in the 1980s and 1990s ...

The COVID-19 pandemic brought messenger RNA (mRNA) vaccines to the forefront of global health care. After their clinical ...

Due to their nanoprecise spacing of adjuvant molecules (shown as green ribbons on one face of their squareblock structures), DoriVac vaccines, after being taken up by antigen-presenting immune cells, ...

The central ingredient of therapeutic cancer vaccines is antigens, which are preferentially produced or newly produced (neoantigens) by tumor cells and enable a patient’s immune system to search and ...

DNA origami and beyond. A) DNA octahedron that inspired development of DNA origami. B) 2D DNA origami (smiley face serves as an example). C) Hollow 3D DNA origami shapes that are folded from 2D ...

A new vaccine design uses folded DNA to steer the immune system toward producing the rare immune cells needed to make protective antibodies against HIV. When you purchase through links on our site, we ...

One of the challenges of fighting pancreatic cancer is finding ways to penetrate the organ's dense tissue to define the margins between malignant and normal tissue. A new study uses DNA origami ...