The American College of Rheumatology (ACR) has issued new guidelines on the treatment of rheumatoid arthritis, addressing questions about initial treatment with methotrexate and minimizing reliance on ...

Methotrexate is usually the first medicine given for rheumatoid arthritis, but certain side effects require immediate medical ...

Methotrexate is a strong medicine. The FDA approved it to treat adults with severe, disabling psoriasis that cannot be controlled with medicine applied to the skin or light treatments. Methotrexate ...

In July 2022, the US Food and Drug Administration (FDA) expanded the labeling of Krystexxa (pegloticase; Horizon Therapeutics), a PEGylated uric acid-specific enzyme, to include coadministration with ...

Patients with Wegener's granulomatosis often undergo treatment with cyclophosphamide in order to induce disease remission. Methotrexate and leflunomide have been proposed for maintaining remission ...

Patients who take methotrexate for a variety of immune-mediated inflammatory diseases and pause taking the drug following receipt of a COVID-19 vaccine dose did not have a higher risk of disease flare ...

Methotrexate belongs to a class of drugs called antimetabolites. This type of drug slows the growth of skin cells or cancer cells and suppresses the immune system. In addition to treating rheumatoid ...

Please provide your email address to receive an email when new articles are posted on . PHILADELPHIA — Discontinuing methotrexate for 1 week after influenza vaccination offers similar seroprotection ...

Methotrexate is a chemotherapeutic agent used as medical therapy for the treatment of ectopic pregnancy. Although it is most commonly administered intramuscularly, obstetricians may inject the ...

Adalimumab monotherapy and combination with methotrexate showed similar drug survival and PASI75 response rates in plaque psoriasis patients. Methotrexate reduced antidrug antibody levels but did not ...

For decades, methotrexate has formed the foundation of therapy in RA, either alone or in combination with other drugs; however, its mechanisms of action remain poorly understood, and many patients ...

Methotrexate significantly lowers systolic blood pressure in newly diagnosed RA patients compared to sulfasalazine, potentially reducing cardiovascular risk. The study provides prospective comparative ...