Molecular diagnostic assay development and design is no simple task, and several factors affect the performance and usability of a test. Diagnostic companies can enhance assay stability and ...

Freeze drying, lyophilization, and cryodesiccation are all terms used to describe the process of removing water from a sample at low temperature. This low-temperature dehydration process maximizes ...

UMass Lowell has opened a state-of-the-art lyophilization facility that will help drive innovation and discovery in biopharmaceutical manufacturing in New England and beyond. Called the Lyophilization ...

Researchers have developed a new method to improve the structural and functional stability and long-term storage of hydrogel microparticles during lyophilization. By using polyethylene glycol (PEG) ...

Vaccines have been proven to be efficacious in controlling the spread of coronavirus disease 2019 (COVID-19). Among the different kinds of vaccines available, mRNA vaccines became the frontrunners in ...

Approximately one-third of the unique biologicals in the FDA’s purple book are lyophilized, according to a recent paper. That includes (in 2020) nearly a quarter of monoclonal antibodies. Trends ...

LyoHUB, a university-industry center at Purdue whose goal is the efficiency, science and technology of freeze-drying in pharmaceuticals and other areas, is offering a new free online course and other ...

Lyophilization, also known as freeze-drying, is a complex process that couples heat and mass transfer for improving the shelf life of moisture labile pharmaceuticals and biopharmaceuticals. The recent ...

Lyophilization is widely recognized as an effective method for increasing the shelf life of labile drugs, including small molecule compounds and biotherapeutics. Of the top 100 drugs, ~16% are ...

Lyophilization is a complex operation used to prepare stable pharmaceutical and biopharmaceutical products through freeze-drying. During lyophilization, the water fraction of the product is reduced to ...

The COVID-19 pandemic put a spotlight on the vaccine supply chain and public health impact of vaccine stability. But Purdue University researchers have been working on the problem for years — using ...