Viruses attack nearly every living organism on Earth. To do so, they rely on highly specialized proteins that recognize and ...
Why some memories persist while others vanish has fascinated scientists for more than a century. Now, new research from the ...
Most mutations that cause disease by swapping one amino acid out for another do so by making the protein less stable, according to a major study of human protein variants that was published in Nature ...
Microglia are the brain's immune cells that clean out debris, such as damaged proteins and old cell parts, to keep the organ ...
Brazilian researchers have identified previously unknown forms of a protein linked to breast cancer. The discovery ...
When a protein folds, its string of amino acids wiggles and jiggles through countless conformations before it forms a fully folded, functional protein. This rapid and complex process is hard to ...
It has long been thought that protein function and stability are highly sensitive to changes in the composition of the internal structures, or protein cores. However, a large-scale experiment probing ...
A recent review article highlights evolving MS-based methodologies that are reshaping ligand discovery and mechanistic characterization for membrane protein drug targets. LCGC International spoke to ...
The Human Domainome 1—the largest library of human protein variants—reveals the cause of certain genetic disorders, paving the way for personalized medicines. “We measured every possible mutation in ...
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