MicroRNA-27a has been shown to stimulate both the wingless-type integration site family, or Wnt signaling, and the bone morphogenetic protein pathways to actively promote bone regeneration, according ...

Nibbler (Nbr) is a 3′-to-5′ exoribonuclease whose catalytic 3′-end trimming activity impacts microRNA (miRNA) and PIWI-interacting RNA (piRNA) biogenesis. Here, we report on structural and functional ...

After years of type 2 diabetes, red blood cells may quietly turn against the heart—offering a new clue for spotting danger ...

Analyzing gene expression can provide a roadmap for deciphering the role of specific genes or elaborating critical players in functional metabolic pathways. Companies are pursuing solutions to better ...

MicroRNAs are essential for Purkinje cells to develop their characteristically elaborate dendritic arbors. When Scripps Research scientists temporarily turned off microRNA function during development, ...

Potential of Field Is Catalyst for Emerging Diagnostic and Therapeutic Strategies As key regulators of gene expression and cellular machinery, microRNAs may be the most significant discovery in ...

The Nobel Prize in physiology or medicine was awarded Monday to Americans Victor Ambros and Gary Ruvkun for their discovery of microRNA, tiny pieces of genetic material that alter how genes work at ...

STOCKHOLM — Two scientists won the Nobel Prize in physiology or medicine on Monday for their discovery of microRNA, tiny bits of genetic material that serve as on and off switches inside cells that ...

The 2024 Nobel Prize in Physiology or Medicine was awarded to Victor Ambros and Gary Ruvkun for their groundbreaking discovery of microRNA and its pivotal role in post-transcriptional gene regulation.