Scientists who work with lipid nanoparticles (LNPs) say they have developed a new type of material capable of reaching the lungs and the eyes. They call their study “Thiophene-based lipids for mRNA ...

LNPs are solid or semi-solid particles at room temperature. They are composed of a lipid core stabilized by surfactants or other agents. This lipid core provides a hydrophobic environment ideal for ...

Bethesda, MD – In response to the growing number of lipids expected to be discovered through lipidomics and in anticipation of the massive amounts of data that will be generated by the lipid community ...

Interest in lipid nanoparticles (LNPs) as delivery vehicles for precision therapies in genetic diseases and cancers remains at an all-time high. Now, scientists from the University of Pennsylvania, ...

“We’ve never had such an in-depth map of the CD1 lipidome available,” said Patricia Barral, an immunologist at King’s College London who was not involved with the work. “It will enable us to start ...

In a recent study published in Cell Host & Microbe, researchers highlighted the role of lipids, especially bacteria-derived lipids in the gut microbiome, in mammalian physiology in the context of ...

Crenarchaeol is a large, closed-loop lipid that is present in the membranes of ammonium-oxidizing archaea. In comparison to other archaeal membrane lipids, crenarchaeol is very complex and, so far, ...

Key presentation unveiled Acuitas’ Next-Generation LNP Advancements, which is designed to enhance potency and safety, expand delivery beyond the liver, and enable broader therapeutic impact Additional ...

In this article, data-dependent acquisition (DDA) experimental data collected by the ZenoTOF 8600 system was analyzed with MS-DIAL 5.5 software to detect and classify lipid molecular species in human ...