Many human traits are influenced by multiple genes. Human genes can also carry slight variations in their gene sequences, which can have a wide range of effects. In some complex traits, those small ...

The Collaborative Cross (CC) mouse resource has emerged as an indispensable platform for elucidating the genetic basis of complex traits. By combining high levels of genetic diversity from eight ...

Sometimes, a small error in the sequence of DNA can lead to a very serious disease. Scientists have identified many mutations ...

A new genetic mapping strategy reveals how entire networks of genes work together to cause disease, filling in the missing links left by traditional genetic studies. The technique could transform how ...

A new genome-wide mapping method finally shows how thousands of genes connect to drive disease. Biomedical researchers are working intensively to identify the genes that contribute to disease, with ...

What makes every person unique? Part of the answer is in our genes. A gene is a basic unit of heredity, the means by which traits get passed from one generation to the next, and genetics is the study ...

Today's biomedical researchers are relentlessly searching for genes that drive disease, with the goal of creating therapies that target those genes to restore health. When a single gene is the culprit ...

Structural variations (SVs)—large-scale changes in DNA sequence—play a crucial role in shaping traits such as yield, quality, and environmental adaptation in crops.

An individual’s genetics and their environment both shape their personality. However, opinions differ on the degree to which each of these factors influences personality, and how they contribute to ...