Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

A study by the Mildred Scheel Early Career Center group led by Dr. Mohamed Elgendy at the TUD Faculty of Medicine provides ...

Neurodegenerative disorders are pressing global health challenges that stem from progressive neuronal dysfunction and loss. While the central roles of ...

In vitro studies pinpoint signaling pathways that could be potential targets in oral squamous cell carcinoma treatments.

This review synthesizes preclinical evidence showing that cinnamon-derived compounds can modulate inflammation, oxidative ...

Pyruvate dictates redox balance and cell size, establishing metabolism as a dominant regulator of cellular fitness, unveiling new strategies to modulate cancer, regeneration, and diabetes.

The researchers used lipid nanoparticles (LNPs) to deliver cyclic GMP-AMP (cGAMP) synthase (cGAS) mRNA to cancer cells. This results in production of the endogenous stimulator of interferon genes ...

Immunotherapy has revolutionized the way physicians treat patients. Previously, chemotherapy was the standard-of-care with the goal to eliminate tumor cells by dysregulating their ability to ...

New research has mapped the cell types that specialize to form reproductive organs in both sexes, identifying key genes and ...

The journey started with an enigma in the zebrafish embryo: some endothelial cells, actively involved in the initial stages ...