For many people diagnosed with cancer, treatment with immune checkpoint inhibitors (ICIs) has dramatically extended lives.

In an experimental trial, a personalized mRNA vaccine was tested in 14 individuals with an aggressive form of breast cancer. It trained immune cells to target cancer-specific mutant proteins, inducing ...

Lung cancer tumor cells in mice communicate with the brain, sending signals to deactivate the body’s immune response, a study finds ...

According to the results of the early study, published simultaneously in the New England Journal of Medicine, 92% of patients who received only an immune-based treatment to help their own immune ...

A protein made by stressed cancer cells helps lung and pancreatic tumors evade the immune system, a new study shows. Led by ...

The so-called guards are tumor macrophages. Under normal conditions, macrophages serve as first responders, helping fight infections and repair tissue damage. Inside tumors, however, these cells are ...

Colorectal cancer has long baffled scientists because, unlike most tumors, patients often do better when their cancers are packed with immune-suppressing regulatory T cells. New research finally ...

“Many confounding factors in real life—including lifestyle, UV exposure, occupational hazards, and immune status—can ...

SLAMF6 is an immune cell receptor whose function was not clear. Does it activate or inhibit cells? The results so far have been contradictory. Now, scientists at the Institut de Recherches Cliniques ...

Researchers at the University of California San Diego have discovered a promising new treatment approach for pancreatic ...

Cancer immunotherapies, including cancer vaccines, harness and amplify the immune system’s natural ability to detect and attack cancer cells. In this illustration, immune T cells (pink) attach to a ...