A distinct signaling pathway called TNF- drives the transformation of epithelial cells into aggressive tumor cells. During cancer progression, cells activate their own TNF- program and become invasive ...
HOXB13, a B-class homeobox transcription factor, sits at the hub of developmental gene networks yet has emerged as a double-edged sword in human cancer. While indispensable for embryonic patterning ...
Even before a tumor in the pancreas becomes discernible, an activated cancer gene actively remodels its future environment ...
A new editorial was published in Oncotarget, Volume 16, on March 10, 2025, titled "EXPOSOMES and GENES: The duo influencing CANCER initiation and progression." In this editorial, Drs. Uzma Saqib, ...
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