A biotech company pioneering transposases for cell line engineering claims to have widened the applications of these tools. Oren Beske, PhD, gave a talk at BioProcess International, about how ATUM is ...

Host Cell Line Selection: The first critical step is selecting the appropriate host cell line. This decision is based on factors such as growth characteristics, genetic stability, and productivity, ...

From analytical control through downstream processes to manufacturing, BsAbs present challenges in protein expression, purity, and stability.

Proteomics-informed, genome-edited CHO design increased productivity up to three-fold and titers two-fold, strengthening CLD for novel biologics and biosimilars. Extended culture robustness was ...

Multibillion-dollar gene therapy market facing critical manufacturing bottleneck that limits reach of lifesaving therapies to patients VectorSelect™ platform has the potential to revolutionize the ...

Widely used as a genome editing tool, the CRISPR-Cas9 system allows researchers to precisely induce frameshift mutations in specific genes or insert foreign nucleic acid sequences into a cell’s DNA.

Cell culture is a fundamental technique in biotechnology and life sciences that involves growing and maintaining living cells outside their natural environment, typically in a controlled laboratory ...

Advances in cell line engineering and microfluidic technologies offer substantial opportunities to shorten timelines in cell line development (CLD). However, as with any innovation, optimizing these ...

Amsbio now offers a ready-to-use range of lentiviral particles designed to deliver target genes into virtually any mammalian cell type, both dividing and non-dividing, in vitro and in vivo. These ...